The Obesity-Cancer Connection
GREAT article today in “Environmental Nutrition.” Here are the highlights:
“Expect to see higher rates of cancer as America packs on the pounds. Overweight and obesity come with plenty of bad news, including aches and pains and increased risks for heart disease, high blood pressure, diabetes, osteoarthritis and several types of cancer.”
Only about half of Americans know that there is an obesity/cancer link. Excess body weight generates as many as 100 substances. Some are hormones and chemicals that set the stage for cancer and other chronic diseases. Here are some of the most dangerous:
1. Estrogen – From puberty to menopause, the ovaries produce estrogen, helping to regulate a woman’s menstrual cycle and enabling normal breast development. A woman’s lifelong exposure to estrogen affects her cancer risk. After menopause, then the ovaries stop producing estrogen, body fat is the major source of the hormone. The more fat a woman has, the more estrogen is pumped into her bloodstream which raises her risk for endometrial and breast cancer.
2. Insulin Resistance. Excess body fat can promote insulin resistance, which many times, leads to diabetes. Higher level of insulin (since the body pumps out more HOPING that it will help sugar levels decrease) “and the resulting increased availability of insulin-like growth factor tends to promote cell growth and reproduction, including that of cells with damaged DNA than can develop into cancer.”
3. Inflammation. Body fat also secretes cytokines, proteins important in the comminucations between cells. An overabundance of fat cells produces an overabundance of cytokines. As they circulate throughout the body, these proteins promote chronic, low-level inflammation, which leads to the production of free radicals than can damage the cells’ DNA and start the cancer process. Additionally, inflammation stimulates the development of new blood vessels that allow cancer cells to grow and then spread.
Just another reason to count the calories, hit the strength training and share this info with those who may be struggling with some form of cancer.
Oh, and get those leftovers out of the house if you are still nibbling!!!
Jim




